Polysulfides Link H2S to Protein Thiol Oxidation
نویسندگان
چکیده
منابع مشابه
Thiol and Mn2+-mediated Oxidation
Horseradish peroxidase has been shown to catalyze the oxidation of veratryl alcohol (3,4-dimethoxybenzyl alcohol) and benzyl alcohol to the respective aldehydes in the presence of reduced glutathione, MnC12, and an organic acid metal chelator such as lactate. The oxidation is most likely the result of hydrogen abstraction from the benzylic carbon of the substrate alcohol leading to eventual dis...
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The health benefits of garlic and other organosulfur-containing foods are well recognized and have been attributed to both prooxidant and antioxidant activities. The effects of garlic are surprisingly similar to those of hydrogen sulfide (H2S), which is also known to be released from garlic under certain conditions. However, recent evidence suggests that polysulfides, not H2S, may be the actual...
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متن کاملS-sulfhydration as a cellular redox regulation
For many years reactive oxygen and nitrogen species (ROS and RNS) have been recognized as key messengers in the process of thiol-based redox regulation. Relatively recently, literature reports began to mention reactive sulfur species (RSS) and their role in thiol regulation. This review is focused on biogenesis and biological properties of RSS, including: hydropersulfides, polysulfides and hydr...
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ژورنال
عنوان ژورنال: Antioxidants & Redox Signaling
سال: 2013
ISSN: 1523-0864,1557-7716
DOI: 10.1089/ars.2012.5041